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Diabetes: Coffee and green tea might reduce death risk

Drinking plenty of both green tea and coffee is linked to a lower risk of dying from any cause among people with type 2 diabetes mellitus, suggests research published in the online journal BMJ Open Diabetes Research & Care.

Drinking four or more daily cups of green tea, plus two or more of coffee, was associated with a 63% lower risk of death over a period of around five years, the findings show.

People with type 2 diabetes are more prone to circulatory diseases, dementia, cancer and bone fractures.

And despite an increasing number of effective drugs, lifestyle modifications, such as exercise and diet, remain a cornerstone of treatment.

Previously published research suggests that regularly drinking green tea and coffee may be beneficial for health because of the various bioactive compounds these beverages contain.

But few of these studies have been carried out in people with diabetes.

The researchers therefore decided to explore the potential impact of green tea and coffee, separately and combined, on the risk of death among people with the condition.

They tracked the health of 4,923 Japanese people (2,790 men and 2,133 women) with type 2 diabetes and an average age of 66 years, for an average of just over five years.

All of them had been enrolled in the Fukuoka Diabetes Registry, a multicentre prospective study looking at the effect of drug treatments and lifestyle on the lifespan of patients with type 2 diabetes.

They each filled in a 58-item food and drink questionnaire, which included questions on how much green tea and coffee they drank every day.

And they provided background information on lifestyle factors such as regular exercise, smoking, alcohol consumption and nightly hours of sleep.

Measurements of height, weight and blood pressure were also taken, as were blood and urine samples to check for potential underlying risk factors.

A total of 607 of the participants didn’t drink green tea; 1,143 drank up to a cup a day; 1,384 drank two to three cups; and 1,784 drank four or more.

As for coffee, 994 participants didn’t drink it; 1,306 drank up to one cup daily; 963 drank a cup every day; while 1,660 drank two or more cups.

During the monitoring period, 309 people (218 men and 91 women) died.

The main causes of death were cancer (114 people) and cardiovascular disease (76).

Compared with those who drank neither beverage, those who drank one or both had lower odds of dying from any cause, with the lowest odds associated with drinking higher quantities of both green tea and coffee.

Drinking up to one cup of green tea every day was associated with 15% lower odds of death; while drinking two to three cups was associated with 27% lower odds.

Getting through four or more daily cups was associated with 40% lower odds.

Among coffee drinkers, drinking up to one daily cup was associated with 12% lower odds of dying; while one cup a day was associated with 19% lower odds.

And two or more cups was associated with 41% lower odds.

The risk of death was even lower for those who drank both green tea and coffee every day:

  • 51% lower for two to three cups of green tea, plus two or more of coffee
  • 58% lower for four or more cups of green tea, plus one cup of coffee every day, and
  • 63% lower for a combination of four or more cups of green tea, plus two or more cups of coffee every day.

This is an observational study, and as such, can’t establish cause.

And the researchers point to several caveats, including the reliance on participants’ subjective assessments of the quantities of green tea and coffee drunk.

Nor was any information gathered on other potentially influential factors, such as household income and educational attainment.

And the green tea available in Japan may not be the same as that found elsewhere, they add.

The biology behind these observations isn’t fully understood, explain the researchers.

Green tea contains several antioxidant and anti-inflammatory compounds, including phenols and theanine, as well as caffeine.

Coffee also contains numerous bioactive components, including phenols.

As well as its potentially harmful effects on the circulatory system, caffeine is thought to alter insulin production and sensitivity.

“This prospective cohort study demonstrated that greater consumption of green tea and coffee was significantly associated with reduced all-cause mortality: the effects may be additive,” the researchers conclude. – The Star

 

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